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  • Safety and Tolerability of Inclisiran

    A pooled analysis of seven relatively short-term ORION studies of inclisiran vs. placebo for lowering low-density lipoprotein cholesterol that assessed safety and tolerability for up to six years showed that inclisiran has similar rates of adverse events, excluding injection site reactions, as placebo treatment and is associated with fewer major adverse cardiovascular events.

  • National Screening Guidelines for Chlamydia

    Reproductive and sexual health providers could reference evidence-based national guidelines for chlamydia screening and care, including guidelines from the U.S. Preventive Services Task Force, the Centers for Disease Control and Prevention, and the American Academy of Family Physicians.

  • A Comparison of Acute Migraine Therapies Using Big Data

    In a big data-driven observational study that compared 3 million treated migraine attacks captured from a migraine diary smartphone app, triptans were found to be the most efficacious treatment class. Among the triptans, eletriptan had the highest rate of success. Consistent with clinical practice and recent consensus statements, the success of triptans was followed by ergots and antiemetics.

  • Best Practices Needed in Screening and Treating Chlamydia

    Chlamydia infection affects more than 1.7 million people each year, making it the most common bacterial STI. Using a screening tool and checklist, a family planning clinic found success in improving the chlamydia screening rate, identifying more cases of the STI, and making patient visits more efficient by reducing time spent on visits.

  • New Study Shows Oral Contraceptives Decrease Risk of Hypothyroidism

    When researchers decided to explore the link between hormonal birth control and the risk of hypothyroidism, they made a surprising discovery: Contrary to earlier evidence, hormonal contraception decreases the risk of developing hypothyroidism.

  • Nitrates in Food Reduce Cardiovascular Risk

    Dietary nitrates, such as in beetroot juice, improve the cardiovascular risk profile, lowering blood pressure and enhancing endothelial function.

  • Mental Health Screening Needed for Optimal Contraceptive Counseling

    Mental health conditions are common among people of reproductive age. Still, both physicians and patients may have misconceptions about using hormonal contraception if patients are diagnosed with depression or other mental health issues. New research suggests that barriers to effective contraceptive use should be addressed, and clinicians need to dispel myths about the negative psychiatric impacts of hormonal contraceptives.

  • Is Brain Impairment Following COVID-19 Hospitalization Worse Than for Other Severe Illnesses?

    The authors of this prospective cohort study with matched controls found that long-term brain health following severe COVID-19 hospitalization was impaired but was similar to hospitalization from other severe diseases.

  • Confidential Contraception for Minors Is Harder to Obtain than Ever

    About half of U.S. states do not allow minors to obtain contraception without parental approval. For adolescents and teens younger than age 18 years, their only confidential option is to visit a Title X clinic, where a federal ruling from decades ago gives them a right to contraception and privacy. But how does this work in practice? Researchers say that it does not work very well — and it is only getting worse.

  • Health Department Increases IUD Provision at Clinics

    Alabama has one of the highest proportions of pregnant people who do not want to be pregnant, many of whom are low-income and live in contraceptive deserts. A new study revealed that a public health commitment to providing intrauterine devices at Title X clinics helped increase access to long-acting reversible contraception across the state.